Potentiality of antibacterial activity of Nonantibiotics with lactam antibiotics Against methicillin resistant staphylococcus Aureus mrsa clinical strain

Abstract

newline Antibiotic resistance is one of the most pressing issues around the newlineworld today and methicillin resistant Staphylococcus aureus MRSA newlineinfection is one such complaint where the standard therapeutic procedures newlineinvolving powerful antibiotics have failed in controlling the infection Due to newlinefailure of the existing antibiotics with ever raising resistant bacterial strains at newlinea matchless rate new line of therapeutic agents with capability to fight against newlineresistant bacterial strains is in demand Under such circumstances apart from newlineregular antibiotics the effectiveness of nonantibiotics plant derived agents newlineand combinatorial therapies have also been investigated some of which has newlinesucceeded as potent antibacterial agents In the present study antibacterial newlinepotency of the nonantibiotics NA troxipide TR and mebeverine Hcl ME newlineisolated fraction IF from plant Blepharis boerhavifolia BB methanolic newlineextract commercial phenolic flavonoid apigenin AP and their combinations newlinewith ampicillin AM and ceftriaxone CEF against MRSA strain have been newlineinvestigated using microbiological assays newline