Oxidation of Aromatic Secondary Alcohols Using Polymer Supported Oxidizing Agent Kinetic and Mechanistic Study

Abstract

This segment begins with the introduction and primary aspects of kinetics like, newlinerate of reaction, rate law, rate constant, importance of chemical kinetics in reaction newlinemechanism, concentration dependence of reaction rate, thermodynamic formulation of newlinereaction rate, significance of thermodynamic formulation of reaction rate, significance newlineof thermodynamic parameters, catalysts, dielectric constants, salt effect, identification newlineof intermediates and products of reaction, newlineSection (B) Oxidation Reactions newlineThis section includes some chromium based oxidizing agent like chromic newlineacid,chromyl chloride, potassium dichromate, pyridium chlorochromate and pyridium newlinefluorochromate etc. newlineChromic acid is recognized to be a flexible oxidizing agent, reacting with newlineapproximately all types of oxidizable groups. The most important use of chromic acid newlinein synthetic chemistry is in the oxidation of primary and secondary alcohols to newlinealdehydes and ketones correspondingly. During the oxidation of primary and newlinesecondary alcohols, the aldehydes formed are fairly easily oxidized, and are converted newlineto the corresponding carboxylic acids.The use of polymer supported chromic acid has newlinesome advantages in yield, purity of product, ease of separation and selective newlineoxidation. The oxidation process ends at product aldehyde only in the case of primary newlinealcohols and in the case of secondary alcohols ends at products ketones only. Studies newlineon oxidation of various substituted alcohols, using polymer supported oxidizing newlineagents is quite merging. Although a large number of reagents are known in the newlineliterature for such transformations, there still appears a need either to improvise the newlineexisting oxidation methods or to introduce new reagents, to obtain better selectivity newlineunder milder conditions. The use and reuse of polymer supported oxidizing agents newlinewithout loss of capacity; easy workup and safety are the major factors of interest in newlinepresent study. newline