Assessment of ovarian reserve and Lipid profile among women with type II Diabetes Mellitus

Abstract

Type II Diabetes Mellitus (DM) is an age related metabolic disorder characterized by hyperglycemia. The factors responsible for hyperglycemia include reduced insulin secretion, decreased glucose utilization and increased glucose production. Nevertheless, the effect of DM on female fertility remains unexplored. Ovarian reserve is an important predictor of fertility. Lack of adequate reserve may manifest in several forms including endometriosis, infertility, etc. An assessment of the ovarian reserve will help diabetic women preserve their reproductive function and also prevent complications related to ovarian depletion. This study was carried out as case control study. The study was carried out in Diabetic Clinics of Sri Balaji Medical College and Hospital. The study population consisted of 200 adult females of which 100 were normal 100 were diabetics. Our study shows that women with diabetes have newlineprematurely aging, ovaries, as demonstrated by an early decline in the levels of AMH and inhibin B. These findings suggest an earlier decline in the ovarian follicle pool compared with non-diabetic women. newline newline