Fabrication of Functionalized Carbohydrate Polymer Based Polyelectrolyte Membranes and their Composites with Phosphomolybdic Acid for Drug Delivery Toxic Metal Ion Removal and Fuel Cell Applications

Abstract

Fabrication of Functionalized Carbohydrate Polymer Based Polyelectrolyte Membranes and their Composites with Phosphomolybdic Acid for Drug newlineDelivery Toxic Metal Ion Removal and Fuel Cell Applications newline newlineThe current thesis is promptly synthesized sulfonated graft copolymers from PC, newlineNaAlg and NaCMC. These graft copolymers were used for fabrication of PEMs for drug newlinedelivery, toxic metal ion removal and fuel cell applications. The thesis includes all the newlinefindings of the research work and their results are addressed in seven chapters. newlineStructure of this Thesis newline newlineChapter 1 summarizes the general introduction to the research problem newlineundertaken. A variety of controlled drug delivery systems for cancer and HIV/AIDS newlinetherapy have been reviewed with up-to-date literature. This chapter also represents a newlineliterature overview on polymeric materials in drug delivery, toxic metal ion removal, and newlinefuel cells . newline newlineChapter 2 focuses on the experimental methods involved in the present work. newlineFirstly, the synthetic procedures for development of three graft copolymers and newlinefabrication of various polyelectrolyte membranes (PEMs) were described. Secondly, newlinedifferent experimental methods used to perform swelling studies, encapsulation newlineefficiency, in vitro release kinetics, metal ion removal, ion exchange capacity, methanol newlinepermeability, and proton conductivities studies are also discussed. In addition, various newlinemodels used to investigate different physicochemical characteristics of PEMs and in vitro newlinerelease kinetics are also inserted. At the end of this chapter, different characterization newlinetechniques involved in the structural characterization of graft copolymers and PEMs are newlinediscussed. UV-visible (UV-Vis.) spectrophotometry, Fourier transform infrared newlinespectroscopy (FTIR), Nuclear magnetic resonance (NMR) spectroscopy Differential newlinescanning calorimetry (DSC), X-ray diffraction (XRD), Scanning electron microscopy newline(SEM), and Electron dispersive X-ray (EDAX) are overviewed here. newline newlineChapter 3 emphasizes the synthesis of sulfonate functionalized carbo