Development of an intelligent Prediction system for vascular aging From the behavior of carotid artery

Abstract

Aging blood vessels are fertile soil in which the seeds of newlinecardiovascular diseases flourish Cardiovascular diseases remain and will newlinecontinue to be the leading cause of death in all countries The profound newlineimpact of age on the risk of occurrence of this disease is due to age associated newlinechanges in cardiovascular structure Wall thickening and dilatation of the newlinevessel lumen artery wall are prominent structural changes that occur within newlinelarge elastic arteries and change in the elasticity of the vessel is a functional newlinechange which occurs during aging This work understands the age associated newlinechanges in the arteries evaluates a strategy to understand those aspects of newlineaging that occur in apparently healthy persons but confer risk for over newlinesubsequent clinical cardiovascular diseases and hence conclude the relation newlinebetween vascular aging and chronological aging newlineThe large elastic artery common carotid artery of about newline71 subjects with age varying from 22 years to 75 years is imaged with the newlineeconomical ultrasound imaging system The movement of the carotid artery is newlinerecorded in transversal as well as longitudinal sections in B mode Time mode newlineinformation is needed along with spatial information for measuring distension newlineand hence B mode is preferred Using image processing techniques the newlineboundary of the vessel lumen is extracted its diameter measured and its newlinedistension stored for each individual subject newline