Effect of vitamin E and selenium feed supplements on performance oxidative stress immunity and heat shock protein expression in broiler chicken

Abstract

The present study was undertaken to investigate the effect of dietary newlinesupplementation of vitamin E and Selenium on the growth performance, oxidative stress, newlineimmunity and heat shock protein expression in Broiler chicken. Two hundred and forty newline(240) day-old commercial Vencobb 400 broiler chicks were randomly divided into four newlineexperimental groups viz. T0 (unsupplemented control), T1 (Vitamin E at 100 mg/kg and newlineSelenium at 0.2 mg/kg), T2 (Vitamin E at 125 mg/kg and Selenium at 0.25 mg/kg) and T3 newline(Vitamin E at 150 mg/kg and Selenium at 0.3 mg/kg) groups of 60 chicks each subdivided newlineinto 3 equal replicates. The experimental birds were offered ad libitum quantities of four newlineexperimental rations either without supplementation or with supplementation of different newlinelevels of vitamin E and selenium from 0 to 7 days, 8 to 21 days, and 22 to 42 days of age. newlineDuring the experiment, weekly body weight and daily feed intake, total body weight newlinegain, total feed intake, feed conversion ratio (FCR), survivability rate, BPEI, various blood newlinehaematological and bio-chemicals constituents, antioxidant enzymes, heat shock protein, newlineimmunity, cortisol, carcass characteristics like dressing percentage, cut up parts percentage, newlinerelative organ and giblets weight, physicochemical properties of breast meat were studied newlineand recorded. newlineThe mean total body weight (g) was 2120.0±33.5, 2292.9±14.7, 2219.0±16.4 and newline2179.9±9.08 and mean total weight gain (g) was 2077.7±14.5, 2250.6±14.7, 2176.6±14.3 newlineand 2137.6±9.08 for T0, T1, T2 and T3 groups, respectively. The mean total feed intake (g) newlinewas 4062.75±0.08, 4156.53±0.77, 4151.91±0.35 and 4117.85±11.67 and the average feed newlineconversion ratios was 1.92±0.04, 1.81±0.01, 1.88±0.04 and 1.87±0.04 for T0, T1, T2 and T3 newlinegroups, respectively. T1 group attained significantly higher (Plt0.05) final body weight and newlinebody weight gain compared to all the other groups. T2 group did not differ significantly newline(Pgt0.05) with T3 group; but, had a significantly higher (Plt0.05) final body weight over T0 newlinegroup. Total feed intake (g) in T1 g