Quality Evaluation of Indigenous Cultivated Ganoderma spp and Catalytic Activity of Biosynthesized Gold Nanoparticles from Marine Algae

Abstract

Mushrooms belonging to the genus Ganoderma are iconic and are extensively used as a newlinefunctional food as well as medicine to promote health. The first part of the research work is on newlineGanoderma species. Owing to its many medicinal properties, therapeutic and nutritional newlinebenefits, mushrooms belonging to the genus Ganoderma are among the most sought after in newlinethe world market. This led to the artificial cultivation of Ganoderma as the wild samples are newlinenot enough to cater to industrial demands. The extensive global usage of Ganoderma related newlineproducts makes this mushroom cultivation very productive and beneficial. Though, many newlineAsian countries are producing Ganoderma at industrial scale, the cultivation of this mushroom newlineis still at an infancy stage in India. Very few researchers in India had made an attempt to newlinecultivate Ganoderma. In the present study, eighteen indigenous cultivated Ganoderma species newlinewere obtained from Indian Institute of Horticultural Research (IIHR). These strains were newlinecollected from different geographical locations across India and were domesticated at IIHR by newlinecultivating them on locally available substrates. In the present work, all the Ganoderma species newlinewere screened for determining their bioactive (total triterpene and polysaccharide) contents, newlinefatty acid composition, absolute and relative quantification of few triterpenes by HPLC and newlineLCMS-QTOF. Also strains were evaluated for their antioxidant, anticancer and antimicrobial newlineactivities. It was interesting to study these strains in terms of qualitative and quantitative newlineanalyses for determining few elite cultivars. As per our knowledge, this is the first study newlinereporting a comparison of chemical constituents and bioactivity of cultivated Ganoderma spp. newlinefrom different origins across India newline