Evaluation of bleeding disorders in canine vector borne diseases

Abstract

The aim of the study was to study the incidence, evaluate the clinical, haematological, biochemical and haemostatic parameters and to assess the appropriate and effective therapeutic regimen for the dogs suffering with bleeding disorders due to vector borne diseases. The study was undertaken with ten apparently healthy animals as control and one hundred and twenty clinical cases with bleeding disorders due to vector-borne diseases for this study. newlineE.canis and B.gibsoni affected dogs were treated standard therapy along with Tranexamic acid, Filgrastim and Enoxaparin sodium had better treatment outcome. This study had proved that Filgrastim was found to be very effective and newlinesuccessful in managing dogs with pancytopenia especially leucopoenia. Filgrastim administration resulted in increase in the peripheral blood leukocyte counts after single administration. Coagulation parameters before and after treatment were compared and they showed a significant decrease in D-Dimer values in Enoxaparin treated group. Thus Enoxaparin was found to be very effective clinical therapy in managing dogs which had both pancytopenia and DIC. newlineKey Words: Canine- E.canis - B.gibsoni Thrombocytopenia - Tranexamic acid Filgrastim - Enoxaparin newline newline