Synthesis characterization electrochemical and biological studies of mannich base and their gallium complexes

Abstract

Hemilabile ligands are the class of chelating ligands, which possess two different types of donating groups, out of two coordinating sites; one exerts only a weak coordination to the metal ion depending upon the environment. These types of ligands are much sought after for their versatile applications in the fields of medicine, catalysis, and supramolecular chemistry. The donating properties of this class of ligands can be electronically tuned by varying the substitutionally on the centre donating sites. Generally, these ligands possess the combinations such as phosphinephosphite, phosphine-amine, phosphine-phosphine oxide in their structures. Metal complexes of hemilabile ligands are useful for catalysis. The weak metal-ligand bonds present in these complexes can be selectively cleaved, when a strong substitution approaches towards the coordination sphere. Such complexes have been used in a range of catalytic reactions due to the hemilabile ligand being able to furnish open coordination sites and stabiliz reactive transition metal centers during the course of a reaction. This reversible protection of one or more coordination sites is the most important property of hemilabile ligands. In this pr ject proposal we plan to synthesize the new P-N ligands from variously substituted 2,6-diphenyl piperidin-4-ones. The synthesized ligands will be characterized by spectral, electrochemical impedance spectroscopy, potentiodynamic polarization and thermal studies. New Ga (III) complexes were synthesized using methyl, dimethyl and ethy substituted 2,6-diphenylpiperidin-4-ones. The synthesized complexes were characterized with spectral, thermal and antibacterial studies. The corrosion resistance of methyl, dimethyl and ethyl substituted 2,6 newline