A Study On Laryngopharyngeal Reflux Disease Association With Mucociliary Clearance And Eustachian Tube Dysfunction

Abstract

The term Laryngopharyngeal Reflux (LPR) was coined by newlineJames and it is widely accepted by the American Academy of newlineOtolaryngology: Head and Neck surgery.[1] Laryngopharyngeal newlinereflux disease (LPRD) was first described by von Leden and Moore, newlinein the 1960, but it did not come to forefront of otolaryngology until newlineKoufman s landmark thesis on this subject in 1991.[1,2] LPR was newlinenot discussed as a separate condition from GERD until the 1960s newlineand 1970s.[3] Laryngopharyngeal reflux disease is extraesophageal newlinevariant of gastroesophageal reflux disease that affects the larynx newlineand pharynx.[4,5] The other terms that are used are extra newlineesophageal reflux , chronic laryngitis and supra esophageal newlinecomplication of gastroesophageal reflux newlineBecause of the high prevalence of the disease and potential newlineserious consequences, it is important to be familiar with newlinecontemporary perspectives on this disorder.[13,17,18] Population newlinebased studies found that the prevalence of symptoms attributed to newlineLPR was in the range of 15% to 20% [19,20]. De Vault (2000) and newlinePostma et al (2002) have stated that up to 15% of all visits to the newlineotolaryngology clinics are because of manifestations of LPR newline[21,22]. newlineIn this study we aim to find if the laryngopharyngeal reflux newlinedisease is a contributing factor for impaired mucociliary clearance newlineand Eustachian tube dysfunction newline