Development and evaluation of fast dissolving oral film for some poorly water soluble drugs

Abstract

Development and evaluation of fast dissolving oral film for some poorly water soluble drugs 445.1 Plan of Works and 61656; Preformulation studies and#61623; Melting point determination and#61623; UV Spectrophotometric analysis and#61623; HPLC analysis and#61623; Solubility determination and#61623; Drug- excipient compatibility studies Fourier transform infrared spectroscopy (FTIR) analysis of Differential scanning calorimetry (DSC) analysis and#61623; pH stability profile and#61656; Preparation of solid dispersion (SDPs) of drugs and#61656; Formulation development of fast dissolving oral films (FDFs) and#61656; Evaluation of SDPs and#61623; FTIR analysis and#61623; DSC analysis and#61623; Percent practical yield and#61623; Percent drug content and#61623; Determination of saturation solubility and#61623; Percent drug dissolution study and#61623; Stability study and#61656; Evaluation of FDFs and#61623; FTIR analysis and#61623; DSC analysis and#61623; Uniformity of mass and#61623; Thickness and#61623; Percent drug content and#61623; Folding endurance and#61623; Surface pH and#61623; Percent moisture uptake and#61623; Percent swelling newlineChapter-5 Plan of Works Development and evaluation of fast dissolving oral film for some poorly water soluble drugs 45 and#61623; Tensile strength and#61623; Percent elongation and#61623; In-vitro disintegration time study and#61623; In-vitro percent drug dissolution or release study and#61623; Stability study and#61623; Surface morphology using SEM and#61623; Ex-vivo permeation study and#61623; In-vivo pharmacokinetic study and#61656; Compilation of findings, data analysis, interpretation and derivation of conclusions. and#61656; Publications and presentations.