Randomized open label clinical study to compare the efficacy of Mansyadi Kwath Shirodhara and Jala dhara in the management of Chittodvega with special reference to Generalized Anxiety Disorder

Abstract

Generalized Anxiety Disorder (GAD) is defined as excessive anxiety and worry occurring on most days for at least six months, concerning a variety of events or activities. The worry is difficult to control and is accompanied by somatic symptoms such as restlessness, fatigue, difficulty concentrating, irritability, muscle tension, and sleep disturbances. newlineGAD is a pervasive psychiatric condition worldwide, with notable disparities in prevalence 35.5% in urban populations compared to 13.9% in rural populations, as indicated by epidemiological studies. According to WHO, mental disorders rank as the third leading cause of disease burden in India. This highlights the profound impact of GAD on physical health, psychological well-being, and social functioning, underscoring the urgent need for effective therapeutic strategies. newlineIn Ayurveda, Chittodvega is described as a manas roga arising from the vitiation of raja and tama in association with vata and pitta. The term derives from chitta (mind) and udvega (anxiety), referring to an anxious or disturbed state of mind. Based on its etymology, classification as a psychological disorder, and symptom overlap, Chittodvega can be correlated with Generalized Anxiety Disorder. newlineShirodhara is a unique, non-invasive Ayurvedic therapy involving the continuous and rhythmic pouring of oil, milk, or Kwath (herbal decoction) on the forehead from a specific height for a defined duration. Despite promising outcomes of Shirodhara in alleviating anxiety and related disorders, significant research gaps remain. In particular, the comparative efficacy of herbal decoction-based Shirodhara (e.g., Mansyadi Kwath) versus plain water-based therapy (Jaladhara) has not been adequately explored, warranting systematic investigation. newlineAim: To compare the efficacy of Mansyadi Kwath Shirodhara and Jala-dhara in the management of Chittodvega (GAD). newlineMethods: A randomized open-label clinical study was conducted on 84 patients (18 60 years) diagnosed with GAD as per DSM-V criteria