Ecotoxicological assessment of Selenium nanoparticles on primary and secondary producers a Transcriptomic approach

Abstract

Many industries, including agriculture, health, and environmental cleanup, newlinehave shown interest in selenium nanoparticles (SeNPs). Nevertheless, worries over newlinetheir possible effects on aquatic ecosystems and the environment have been newlineheightened by their growing use. This study provides an in-depth analysis of the newlineecotoxicological effects of SeNPs on two key species within aquatic ecosystems: newlineChaetoceros gracilis, a primary producer, and Dioithona rigida, a primary newlineconsumer. A thorough investigation of the environmental behavior, hazardous newlineprocesses, and long-term ecological effects of SeNPs is necessary in light of these newlineresults. newlineSeNPs are widely used in medicine and agriculture, but they pose newlinesignificant risks to environment given their potential toxicity. Owing to their small newlinesize, large surface area-volume ratio, and profound chemical activity, nanoparticles newlinepose risks that come with their mechanistic interactions with biological systems. Of newlinetop concern is the bioaccumulation and toxicity in aquatic organisms, including newlinethose at lower trophic levels with potential cascading impacts through an newlineecosystem. As far as we could possibly know, this study is a huge contribution to newlinefill the gap on acute and chronic toxicological effects of SeNPs specifically in newlinemarine species represented by D. rigida and C. gracilis. newlineThe research was conducted in a systemic manner making full use of newlinevarious techniques to synthesize and characterize SeNPs such as UV-Vis, HRTEM, newlineDLS, Zeta potential analysis, Raman spectroscopy and XPS. These approaches newlineconfirmed that the SeNPs were spherical, polydisperse in character showing a newlinenegative surface charge and stability, therefore suitable for environmental newlineinteraction potential. newlineCytotoxicity analysis on C. gracilis presented large decrease in cell viability newline(14.63 mg/L after 96 hours/ LC50).