Synthesis Characterization and Biological Evaluation of Metal Oxide Nanomaterials

Abstract

Nanomaterials have attracted a great deal of attention from the scientific community due to their unique properties and applications. The small size metal oxides have opened up the door for intensive research to utilize their properties for biomedical applications. Silver nanoparticle (Ag NPs) and metal oxide nanomaterials like MgO, ZnO, NiO and its silver doped nanocomposites(Ag-MgO, Ag-ZnO, Ag-NiO)have been prepared using solid state combustion method using poly vinyl alcohol(PVA) as a fuel. The structure of as prepared oxides and its silver doped nanocomposites were characterized using X-ray diffraction (XRD) tool and morphology by Scanning Electron Micrograph (SEM) tool as well as Transmission electron micrograph tool respectively. Presence of the metals in the oxides and its Ag composite was confirmed by the EDX pattern. Bonding nature in the composite is well studied by the Fourier transform infrared (FT-IR) tool. Antibacterial activity studies of the nanocomposites are carried out against various bacteria. newlineMetal oxide nanoparticles have widely attracted researchers due to their potential applications in a variety of fields, especially medical importance. In the current study, monometallic oxides like CuO and MnO2nanomaterials and bimetal oxide CuMn2O4 nanoparticles were successfully synthesized by combustion route. Doping of metal oxides nanoparticles with the specified bioactive metal dopent s results in significant improvement of essential biological properties and advanced features. Combustion derived CuO, MnO2and CuMn2O4were subjected for antimicrobial activity studies. Obtained resultsreporting that, biologically active CuO and MnO2nanoparticles on doping that result as CuMn2O4nanoparticles possess high antimicrobial activities. From the zone of inhibition studies it was evident thatdopingplays akey role inthe enhancementof the antibacterialand antifungal activity of CuMn2O4nanoparticles. As a result of this study one can predict CuMn2O4nanoparticles may lead to new advanced research in biomedical app