optimizing lignocaine dosage non inferiority of low volume lignocaine in ultrasound guided sciatic nerve block

Abstract

ABSTRACT newlineBackground and objectives newlineThe sciatic nerve in Popliteal fossa is Popliteal sciatic nerve block for newlinesurgeries below the knee. Ultrasound guidance reduces the complication, improved newlinequality of regional block. Subpar neural injection produces better success rate and newlineincreased duration of blockade. Lignocaine is commonly used local anaesthetics and newlineadrenaline prolongs the duration of drug. Addition of buprenorphine increases local newlineanesthetic effect. The primary objective is to compare duration of sensory blockade in newlineultrasound guided Popliteal sciatic block by low vs conventional 1.5 %lignocaine. newlineMATERIALS AND METHODS newlineA NON inferiority trial was employed involving 40 patients. Patient was newlinerandomized into 2 groups. Group 1 had 1.5% lignocaine and adrenaline 16ml. Group newline2 10ml 1.5% lignocaine with adrenaline. This Non inferiority trial include ASA 1, 2 newlineand3 undergoing lower limb surgeries. Popliteal sciatic nerve block performed using newlineUltrasound guidance in lateral approach. Sensory block evaluated by pin prick, newlineduration of sensory block and patient satisfaction was documented newlineRESULT newlineThe result indicated that low volume 1.5% lignocaine with adrenaline 10ml is newlinesufficient compared to conventional volume 16ml 1.5% lignocaine. Low volume newlineproduced efficient duration of block and helps in reduction of neurotoxicity. newlineDemographic data, anesthetic protocols, and parameters were established. newlineCONCLUSION newlineStudy concluded that duration of low volume 10ml 1.5% lignocaine with newlineadrenaline was Non inferior to Conventional volume 16ml lignocaine 1.5%with newlineadrenaline in Ultrasound guided popliteal sciatic nerve block. newlineKeywords newlinePopliteal sciatic nerve block, Ultrasound, lignocaine with adrenaline, lower newlinelimb surgeries newline