Isolation of Bioactive Compound from Microorganisms for the Inhibition of Pancreatic Lipase and Cholesterol Esterase Potential Targets for Antiobesity

Abstract

Obesity is considered as one of the global health issues. It has become a major newlineconcern worldwide and directly contributes to many chronic illnesses such as newlinecardiovascular disease, diabetes and hypertension. Increase in body weight is the newlineoutcome of an imbalance between the amount of energy intake and energy expenditure, newlineby which the excessive energy intake is accumulated as Triacylglycerol in adipose newlinetissue. The two pivotal enzymes pancreatic lipase and cholesterol esterase play newlineimportant role in the metabolism of lipids newline