Analysis of the effect of estradiol on synaptic proteins and neuroinflammatory markers in unilateral and bilateral ovariectomized wistar albino rats

Abstract

newlineTo investigate the effect of estradiol on Synaptic proteins and neuroinflammatory newlinemarkers in unilateral and bilateral ovariectomized wistar albino rat models newline2.2 The objectives of the study are newline1. To investigate the effect of estradiol on behavioural parameter, estrogen levels in newlineunilateral and bilateral ovariectomized wistar albino rat models newline2. To study the impacts of estradiol on the expression of Synaptic proteins newline(Synuclein, SNAP25, PSD-95 and Neuroligins) and neuroinflammatory markers newline(MMP-9 and IL-6) in unilateral and bilateral ovariectomized wistar albino rat newlinemodels newline3. To study the histopathology of brain in unilateral and bilateral ovariectomized newlinewistar albino rat models