Second Line Anti Tubercular Drug Resistance and Proteomic Analysis of Mycobacterium tuberculosis

Abstract

newline Tuberculosis (TB), caused by Mycobacterium tuberculosis complex (MTBC), newlineis the ninth leading cause of death worldwide and the leading cause from a single newlineinfectious agent, ranking above HIV/AIDS with a death toll of almost 1.3 million in newlineHIV negative patients. Globally the emergence of multi drug resistant TB (MDR-TB) newlineand extensively drug resistant TB (XDR-TB) has increased the concern of public newlinehealth agencies. The emergence of drug resistance has hindered the effective newlinetreatment in patients with active M. tuberculosis.